Optimization of Replacement Heart Valve Leaflets

This invention provides geometry optimization of heart valve leaflets in transcatheter aortic valve replacement. To expand this technology to younger, lower-risk patients, long-term durability should match the current preferred treatment option, surgical aortic valve replacement (SAVR). Mechanical stress on heart valve leaflets is linked to leaflet degeneration. In this technology, parametric optimization studies are used […]

Noncompetitive Inhibition of MtFBA by 8-Hydroxyquinoline-2- Carboxylic Acid and Derivatives for Tuberculosis Therapeutics

The use of 8-hydroxyquinoline-2-carboxylic acid as an inhibitor against M. tuberculosis class II 1,6-biphosphate aldolase (MtFBA) was found to be a novel and effective alternative to existing antibiotic options. Previous class II FBA inhibitors either lacked specificity or druglike properties to be considered for further drug development. The MtFBA inhibitory and chemical attributes of 8-hydroxyquinoline-2-carboxylic […]

Motor Task Detection Using Brain Subthalamic Nucleus Local Field Potentials

Current deep brain stimulation (DBS) devices are open-loop, meaning that the stimulation signal parameters are adjusted by a clinician and fixed for each patient until the next visit. A closed-loop DBS system, which requires the ability to detect asynchronous behavior in real time, can optimize the therapy by modulating the parameters based on the patient […]

Mobile Self-Leveling Landing Platform for VTOL UAVs

This invention is a semi-autonomous mobile self-leveling landing platform designed to launch, recover and re-launch VTOL UAVs without the need for human intervention. This landing platform is capable of self-leveling on rough terrain and inclined slopes, and it can autonomously operate in remote locations for extended periods of time using large onboard lithium batteries and […]

Miniature Radar System for UAV-Based Air to Air Identification

This invention is a lightweight radar system for use on a small-scale aircraft, namely a miniature unmanned aerial vehicle. Compared to UAVs used by the military, civilian UAVs are often operated by pilots without formal training, and hence they require increased levels of autonomy and intelligence, especially with regard to reducing threats to public safety. […]

Micromechanical Resonators

These resonators, which operate through thermal-piezoresistive transduction, are smaller, more integrated and higher resolution replacements for traditional piezoelectric mechanical resonant sensors. The temperature instability of silicon has been a drawback to its use, but this patent allows for fine tuning of the resonator’s stability by changing the operating bias current and doping the actuator beams. […]

Intelligent Self-Leveling and Nodal Docking System

The Intelligent Self-Leveling and Nodal Docking System (ISLANDS) is a docking platform to be used for landing and take-off of unmanned helicopters and VTOL aircraft. CeCe Ging techtransfer@du.edu 303-871-4230

In plantae production of heterologous proteins using viral amplicons

Heterologous (not in the original host) production of proteins has historically been accomplished in a variety of hosts including bacteria, yeast, and even mammalian cells. However, depending on the properties of the protein, certain hosts may require laborious methods or protein production may not even be possible. A method that enables the use of plants […]

Image Processing for Pose Estimation

This invention provides real-time, GPU-based pose estimation of an unmanned aerial vehicle (UAV) for autonomous takeoff and landing. Visual sensors can be successfully used during the landing process since they are able to provide the pose with an accuracy typically greater than GPS, sufficient to complete the autonomous landing task. CeCe Ging techtransfer@du.edu 303-871-4230

Frequency Shift Keyed Continuous Wave Radar

This invention is a radar apparatus to be used in target detection and/or avoidance on an unmanned aerial vehicle. The radar apparatus may include a microwave front end configured to transmit and receive RF signals, an analog signal conditioning module coupled with the microwave front end module that conditions RF signals received at the microwave […]