VitalScout(SM) Enhanced Early Warning System

VitalScoutSM is Automated Early Warning System (EWS) offering visualization of key data presented as intuitive color-coded alerts that address traditional and costly barriers to the identification and interventions for early signs of deterioration on medical/surgical units in a hospital setting. This innovative technological program embedded within the EHR to mitigate contributing factors for failure to […]

Vascular Arm Sleeve

Vascular access procedures, including IV insertion and catheterization, are among the most commonly performed and important procedures. Despite the frequency of performance, these are technically difficult procedures that many experienced caregivers have difficulty with. This invention is a vascular training sleeve that mimics arm vasculature and can be worn over a live subject. Because the […]

Treatment of Nervous System Injury and Neurodegenerative Disorders and Related Conditions Using a Condroitin Sulfate Proteoglycans Reduction Peptide

Chondroitin sulfate proteoglycan (CSPG) is the major components of scars, which increases significantly after injury/trauma to both peripheral nervous system (PNS) and central nervous system (CNS). Currently, there is no clinically applicable strategy to reduce CSPG. The designed CSPG reduction peptide (CRP) includes an N-terminal cell membrane-penetrating domain, a central CSPG binding domain, and a […]

Trabecular Suppression CT Reconstruction w/ MRI Weighting

The augmented reconstruction algorithm accentuates the soft tissue components of bone marrow, allowing direct visualization of the bone marrow and high tissue contrast format and detection of lesions that are occult with conventional CT reconstruction using conventional single energy CT acquisitions. Computed Tomography (CT) Scans are widely used for visceral organ imaging such as monitoring […]

TIMP3 as a VEGF Inhibitor

Angiogenesis is the process of new blood vessel formation from pre-existing ones. Vascular endothelial growth factor (VEGF) can induce angiogenesis and vascular leakage in the eye, which can lead to retinal diseases. The present invention relates to the use of peptides comprising tissue inhibitor of mettaloproteinases-3 (TIMP3) to substantially inhibit VEGF binding to VEGF receptor-2, […]

Simulated Synthetic Colon

A colonoscopy is a very important and regularly conducted procedure that requires practice to develop technical skill. This device is a synthetic silicone colon that simulates a human GI tract and allows for realistic simulation of endoscopic procedures. The model realistically recreates human anatomy so trainees and physicians can practice difficult cope maneuvers and endoscopic […]

PHASTER: Proximal Hybrid Aortic Stent graft for Thoracic Extended Repair

Novel stent graft device to facilitate easier extended repair in open arch patients with aortic dissection not currently able to treat with fenestrated grafts. Class II device Design Freeze on implant Performance Testing alignment with FDA (DES table/FDA discussions) Looking to finalize manufacturing partner Working towards FIM data, with end goal of regulatory clearance Torey […]

MyFHH

An EMR integrated, web-based, patient-entered family history disease collection and risk stratification platform which delivers evidence-based, clinically actionable decision support to clinicians at the point-of-care. MyFHH is a collaborative effort of Cleveland Clinic’s Genomic Medicine Institute, Learner Research Institute and Center for Personalized Healthcare, Medicine Institute. MyFHH was developed to respond to the current inconsistent, […]

Method of Treating Genitourinary Disorder Using Mesenchymal Stem Cells and Cultured Media

The invention details a novel, noninvasive method to treat stress urinary incontinence (SUI) and other pelvic floor disorders using bone marrow-derived mesenchymal stem cells (BM-MSCs) and their secreted cytokine proteins that have been cultured into a media endowed with therapeutic properties. Repair and regeneration effects are promoted upon intravenous administration for structural and functional recovery […]