Selective Preparation of [6]- and [8]Cycloparaphenylene:Substructures of Carbon Nanotubes

Method of producing Cycloparaphenylenes Scalable production methodology Cycloparaphenylenes are a precursor to carbon nanotube production and have unique electrical propertiesAbstract A synthetic methodology to prepare 6- and 8-cycloparaphenylene, which are short slices of carbon nanotubes. Cycloparaphenylenes are possible precursors for homogeneous synthesis of carbon nanotubes. Further, cycloparaphenylenes have unique electrical properties and can enable armchair […]

Quantifying SARS-CoV-2 Infection Risk Within the Google/Apple Exposure Notification Framework to Inform Quarantine Recommendations (UA21-047)

University of Arizona researchers have developed an improvement to existing COVID-19 contact tracing technology via a multi-variable analysis of distance, volume of exposure, and likelihood of infection to give the user a personalized recommendation for self-quarantine. There are several other apps that have used the Google/Apple API and open source code to develop and improve […]

Primers, Probe and Methods for Mycobacterium Tuberculosis Specific Diagnostics

Diagnostic assay for the detection of Mycobacterium Tuberculosis (MTB) Sensitive and specific primers and probes Effective amplification methodology enables detection of low level infectionsAbstract The invention is comprised of a novel set of primers and probe and an amplification method that enables highly sensitive and specific detection of Mycobacterium Tuberculosis (MTB). The assay can distinguish […]

Preventing the Induction of Fatty Acid Oxidation in Response to S6K1 Inactivation

Dr. David Plas and his lab have identified a new method that enhances cancer cell cytotoxicity when used in combination with Rapamycin. Although Rapamycin suppresses glycolysis in cancer cells, the cytotoxic benefit of Rapamycin is unexpectedly low in many cancers. Agents that inhibit fatty acid oxidation in tumor cells can compensate for this shortcoming by […]

Predictive Modeling of People Movement and Disease Spread on Campus under COVID and Pandemic Situations (UA21-051)

This invention provides university policy makers a novel simulation based on a student-mobility model (a GIS map overlaid with daily student schedules including classrooms, buildings, dorms, etc.) in tandem with a disease propagation model (showing student health, shedding rate of the disease, number of infected students in various locations, probabilities of disease transmissions, etc.) so […]

Optoelectric control of solid-state nanopores

Modulate translocation of molecules through nanopores Applicable to sequencing of nucleic acids Can be used to unblock clogged nanoporesAbstract Nanopore technologies are pushing the boundaries of biomolecule sensing and form the basis of 3rd generation sequencing techniques. Nanopores allow for long read sequencing of DNA and RNA polymers and are extending into protein detection. Solid-state […]

Non-invasive Detection of Spreading Depolarizations

Non-invasive Using excisting technology Dr. Jed Hartings has discovered the unexpected ability to detect spreading depolarizations of the cerebral cortex using non-invasive scalp electroencephalography (sEEG). Spreading depolarizations are pathophysiologic waves that occur spontaneously in the brain following neurological insults such as brain trauma or stroke. They are believed to cause further brain damage. In patients […]

Natural Plant-Based Hand Sanitizer (UA20-229)

University of Arizona researchers have developed a combination of plant-derived extracts formulated to mitigate bacterial and viral pathogens. This combination can to be used as a natural hand sanitizer. Background: Microorganisms like bacteria and viruses are found on every surfaces. Hand sanitizer is a quick and convenient way to kill the bacteria and viruses encountered […]

681: Medical Imaging Systems

Therapeutic Area: Dermatology; Other Technology Platform: Imaging & Sensors Development Stage: Prototype Surgeons operate without the full benefit of modern molecular technology when it comes to locating specific tissue to resect or to avoid injuring. Current practice relies almost exclusively on viewing the operational field with light of the visible spectrum. However, in combination with […]