A Metal Reducing Enzymatic Tag for Optical and Electron Microscopy

Colorado State University Background In academic research and pharmaceutical R&D, there is a demand for high resolution, non-disruptive imaging modalities. Contrast ultimately defines the ability to distinguish a component of interest from background. The development of a cloneable, consistently sized, nanoparticle tag for microscopy represents a significant advancement in the field allowing for greater contrast […]

Ivermectin-Treated Bird Feed to Control West Nile Virus Transmission to Humans

Colorado State University Background West Nile virus (WNV) is an arthropod-borne flavivirus, and the leading cause of domestically acquired arboviral disease in the United States, resulting in significant disease and death every year in humans, domesticated animals, and wildlife. From 1999-20176, >485,000 cases of human WNV disease and >2000 deaths were reported to the CDC, […]

GRAS Material Nanoparticles for Encapsulation and Delivery of Active Pharmaceutical Ingredients

Princeton University Technology Overview Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nano-encapsulation process using generally recognized as safe (GRAS) material. Through this novel synthesis process, components of the core and coating are kinetically assembled in a continuous, low-energy, self-contained micromixing system. The process uses amphiphilic, water-insoluble […]

Theragnostic System for the Directed Diffusion of Therapeutic and Image Agents to Cancerous Cells

Universitat Politècnica de València Background Problem solved by the invention: Intravenous administration is the most frequently used route for parenteral cancer drug delivery. However, it is certain that for some types of highly focalized cancers, this way of chemotherapy administration can lead to serious toxicity-related side effects, which drastically limits the dosage and therefore hinders […]

Vision-Based Fatigue Crack Detection Using Feature Tracking

University of Kansas Background Detecting structural impairments of in-service physical structures such as bridges and roadways is necessary to ensure their continued functionality and to allow for timely repairs. Early knowledge of such structural impairments also helps prevent catastrophic damage due to factors such as corrosion, fatigue, and unexpected loading conditions such as natural disasters […]

Reactor for Performing Chemical Reactions at High Pressure Incorporating Ultrasonic Mixing

University of Kansas Technology Overview KU workers have invented a high-pressure reactor equipped with an internal ultrasonic mixer that is useful for preparing nanomaterials and for conducting reactions with ozone and other reactive gases. The apparatus facilitates the use of supercritical carbon dioxide (CO2 ) as a solvent, allowing the advantages of the solvent properties of […]

Conversion of Biomass to Specialty Chemicals by Lignin Depolymerization

University of Kansas Background Agricultural biomass is largely composed of lignin and cellulose. The cellulose is often used as a feedstock for fermentation, which produces ethanol or other fuel products. However, there is currently no viable commercial solution for valorizing the lignin. It is typically considered a low-value waste and is often burned to produce […]

Environmentally Friendly Navigation Techniques

Background: Current navigation systems offer “shortest-distance” or “shortest-time” functions to help avoid traffic congestion but neither of them determine the most fuel efficient route. With rising gas prices and vehicle emissions, a more advanced navigation system with additional functions, such as an environmentally-friendly feature, is needed. This accomplishment can make a huge improvement on increasing […]

BIOLOGICALLY-INSPIRED MEDIATION OF THE SIZE, SHAPE AND PHASE OF METAL OXIDE NANOSTRUCTURES

More and more chemicals of various origins are being discharged into our local water streams, ending up at waste and water treatment facilities. These chemicals comprising of pharmaceuticals, personal care products, and other various industrial chemicals are currently not removed by typical wastewater treatment practices. UCR Professor David Kisailus and his research team have developed […]