Adjustable Connection for Structural Member

University of Notre Dame Background In architecture, structural engineering, and construction, connections between structural members are typically individually designed for each joint in each structure. Structural members are affixed together in a variety of ways including bolts, rivets, welds, and sometimes incorporating plates. Individually creating each connection in each structure, which is typically one-of-a-kind, results […]

Intranasal Leptin to Treat Opioid-Induced Respiratory Depression (OIRD) in Obese Patients

George Washington University Background Respiratory depression is the leading cause of morbidity and mortality associated with opioids. Patients with obesity experience pain and need opioids more frequently than normal-weight individuals. Chronic consumption of opioids is associated with addiction, physical dependence, and tolerance. Tolerance leads to the requirement of higher doses of opioids for hospital procedures. […]

CaGes – Cancer Gene Signatures Computational Tool

Mount Sinai Health System Background Cancer patients that present similar clinical features can have drastic differences in response to the same treatment. An additional challenge, the initial treatment may have limited efficacy once the tumor becomes resistant. Scientists have made great strides in understanding cancer at the genetic level and how these differences in cancer […]

Hand Interfaces: Using Hands to Imitate Objects in AR/VR for Expressive Interactions

University of California, Los Angeles Background Virtual and Augmented Reality (AR/VR) systems allow users to interact with a virtual environment in an immersive and intuitive way. Typically, a headset provides visual and auditory input to this virtual environment while physical controllers are used as means to interact with this virtual environment. These controllers are often […]

Novel Liposomal Dry Powder Aerosol Inhalation

Virginia Commonwealth University Background Airway mucus obstruction is a hallmark of various pulmonary diseases, such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF). Aerosol inhalation is commonly used in lieu of oral and intravenous antibiotics for chronic infection management. Dry powder inhalers (DPI) are an attractive form of aerosol inhalation for pulmonary […]

MicroRNA Treatment for Traumatic Osteoarthritis

Virginia Commonwealth University Background Osteoarthritis (OA) is a debilitating degeneration of articulating joints in humans. The disease is driven by mechanical instability from traumatic injury or overuse and inflammatory signaling from the cells in local tissue environment. OA is characterized by cartilage degradation as a result of chondrocyte apoptosis, and osteophyte or bone spur formation […]

CERN Technologies for Quantum

CERN Background Quantum technologies have the potential to revolutionise science and society by providing solutions to some problems that are beyond the limits achievable with classical systems. Many of the engineering challenges involved in the design and development of quantum technologies are similar to those faced in high-energy physics, such as extremely precise timing and […]

COVID-19 Tracking

Colorado State University Background The global COVID-19 pandemic is easily spread by people in close proximity, especially in crowds with mobile individuals (e.g., city centers). A widely accepted strategy to mitigate its spread is social distancing, avoiding crowded areas. There is an urgent need for different mitigation strategies to slow the spread of this disease. […]

Real-Time Imaging of Previously Unseen Protein Structures

Okinawa Institute of Science and Technology (OIST) Background The global protein imaging market size is projected to reach USD 1.7 billion by 2025, at a CAGR of 8.9%. The growth in this market is attributed to the increasing adoption of protein therapeutics, technological advancements in protein imaging instruments and consumables, and the increasing focus on […]

Antiviral Technology for PPE Coating and Environmental Sterilisation

NUI Galway Background Protecting healthcare workers is pivotal for control of SARS-CoV-2, yet infection rates amongst this cohort are high (26% of cases in Ireland). A recent study from Zhongnan Hospital of Wuhan University (Ye et al. 2020) demonstrated high levels of viral contamination on items such as PPE, printers, keyboards, doorknobs and hand sanitisers. […]