TT-PINN: A Tensor-Compressed Neural Partial Differential Equation Solver for Edge Computing

University of California, Santa Barbara Background Physics-informed neural networks (PINNs) can be used to solve a wide range of problems involving partial differential equations (PDEs) that are applicable to fluids mechanics, materials modeling, safety verification, control of autonomous systems, and much more. Multilayer perception (MLP) architecture is effective in learning complex systems, but large neural […]

Sparse Entrance Detector Array for MR-Linac

University Health Network Technology Overview The Elekta MR-Linac combines an MR-scanner with a linear accelerator capable of delivering a 7 MV photon beam. Conventional measurement devices cannot be used for the routine quality control (QC) of the MR-Linac as they might not be MR compatible and/or they might not satisfy the specific delivery features of […]

Augmented Reality System for Surgical Planning, Intervention, Guidance, and Education

University Health Network Technology Overview Traditional surgical navigation systems, present virtual models on a separate display away from the surgical field. This AR system provides enhanced guidance directly on surgical field or fused with physical objects. The AR system also provides real-time metrics on pre-operative plans for procedures such as guided osteotomies and out of […]

3D Endoscopy

University Health Network Background In medical practice, radiological and endoscopic/optical imaging each supply complimentary and unique clinical information. Radiological imaging measures bulk tissue properties supplied in 3D spatial coordinates that accurately match those of the physical subject. However, it has insufficient contrast and resolution to identify clinically important mucosal information. Endoscopic optical imaging (i.e. white […]

Nanodisc-Forming Charge-Free Synthetic Polymers

University of Michigan Background Lipid nanodiscs have been shown to be useful in the extraction and research of membrane-bound proteins and are a promising drug delivery technology. These systems use a polymeric “belt” to encircle a cluster of lipids to form the nanodisc structure. Although peptide-based polymers are common, recent studies have demonstrated the use […]

Intra-Operative Eye-tracking System

University Health Network Background Eye-tracking has made its way into healthcare in the fields of radiology and pathology to evaluate expert gaze patterns. The application of eye-tracking in the surgical field still needs development and there are potential benefits of using gaze-tracking in the surgical field. There is still a gap in the literature in […]

GPS for the Surgeon (Pelvis)

University Health Network Technology Overview The GTx-Sarcoma research program (sarcoma surgical team and the GTx engineers/physicists) has developed an image-guided surgery system (“GPS for the surgeon”) for improving the accuracy of complex tumour resections in the pelvis in order to improve treatment outcomes and patient quality of life following surgery. The system consists of planning […]

Low-cost, stable, and easy-to-use guide for accurate intraventricular access with minimal footprint

A single-use device which assists in stereotactic catheter placement into the cerebral ventricles and draining of cerebral spinal fluid (CSF) Problem: Hydrocephalus leads to increased intracranial pressure and an external ventricular drain (EVD) or ventricular-peritoneal shunt (VPS) is needed to drain excess CSF. However, the success of EVD/VPS requires the accurate catheter placement. Currently, freehand […]

A homogenous self-heating, temperature-regulating composite material

A cost-effective homogenous, composite material provides sustained heat at a desired temperature for point-of-care diagnostics and other applications.  Problem:  Point-of-care (POC) diagnostic tests have the potential to greatly enhance patient care and accessibility by reducing the time and equipment necessary for testing. Many current POC tests require 30-40 minutes of stable temperatures which, in turn, requires expensive and complex heating platforms that limit wide-scale use of POC tests.  A reliable, safe heat-source that maintains fixed temperature would […]

Method to determine risk of preterm birth

Problem: Preterm birth accounts for ~12% of all births in the US and costs an estimated $26.2 billion each year. Current methods for identifying patients at risk for preterm birth rely on socioeconomic, behavioral, and clinical factors such as age, tobacco use, or previous preterm birth, respectively. Although there are numerous factors known to be […]