Basic Science to Design Better Drugs (Tarakhovsky)

Immunologist Sasha Tarakhovsky is studying the role of SARS-CoV-2 Nucleocapsid Phosphoprotein (NP) on virus-induced cell death in infected cells. He has identified the likely viral protein responsible for this effect and is working to understand the mechanism, with a goal of finding ways to prevent its occurrence. His work suggests that inhibitors that target proteins of the BET family may be useful targets, and these will be tested in collaboration with Charlie Rice. Alexander Tarakhovsky alexander.tarakhovsky@rockefeller.edu 212-327-8000