University of Manchester Innovation Factory Background
This technology provides a universal solution to delivering multi-wavelength and high-intensity light to samples positioned inside a NMR spectrometer magnet. With this exciting new technology new smart materials, molecular photo-switches, photo enzymes, light-controlled gene expression and drug release, photo-chemical reactions, can be watched, studied and characterised in action by NMR.
This uniquely designed NMR insert and new illumination principles are compatible with a wide range of standard NMR spectrometers and probe heads, and can be retrofitted or added to the equipment of the future. Given that life around us depends and relies on light, studies of photo induced phenomena using one of the most powerful analytical techniques are essential for a wide range of applications. The designer, says: “An NMR spectrometer magnet is generally a very dark place where light never shines, unless you bring it there. The technology are not constrained by any limitations of thin optical fibres – it is much more efficient to place LEDs next to the sample tube, as done here. The trick is how to illuminate a thin sample from the outside, in a very narrow channel, without compromising the probe head. This technology has solved this problem. The sample just glows when the light is switched on.
Sample illumination principles are compatible with anystand ard solution NMR spectrometers and probe heads, including cryo probes.
Suitable for bench top or high field NMR spectrometers.
Can be incorporated into new designs, or retro-fitted.
Ensures high intensity light is delivered to the NMR sample,and uniform illumination of the sample from the outside.
Filling and sealing of NMR tubes can be done as usual:no fiddly optical fibres to insert into samples, no contamination for oxygen sensitive or moisture sensitive samples.
No interference with the workings of the spectrometer,insignificant effect on samples himming and solvents uppression.
Allows full light control from the spectrometer, and potentially full automation and high sample throughput.
University of Manchester Innovation Factory are interested in discussing business and investment opportunities this technology with instrument manufacturers and others.