Distortion Correction for Posterior Segment OCT

Glaucoma is a chronic, degenerative, permanent eye disease, which increases with age and ultimately causes blindness if untreated. The number of people with glaucoma worldwide is expected to rise from 64 million to 111 million in 2040. Africa and Asia are expected to be affected more heavily than the rest of the world. To both detect and determine the progression of glaucoma, optical coherence tomography (OCT), a non-invasive imaging technology is utilized. OCT generate a 3D representation of the tissue structure on the micron scale, bothin vivoand in real-time. However, the generated OCT images are affected by various factors that result in nonlinear image distortions, thereby impacting the 3D interpretation of the images. These distortions are amplified when human OCT devices are used in small animal eyes for animal research. Currently, there is no commercially available OCT device that provides anatomically correct (undistorted) OCT images. Sathya Balachander sathyab@uab.edu (205) 975-6851

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