Molecularly Imprinted Polymers – IP 1551

Detection of ultra-trace level ofcontaminants in complex food, biological and/or environmental samples is oftennecessary for health and safety reasons. Unfortunately, such detection is oftendifficult, due to a variety of reasons, including the complexity of the samplesthat are being tested, and the presence of numerous potential interferents inthese samples. MIPs are synthetic polymeric materials that possess specificcavities complimentary to the shape, size, and functional groups of a template moleculeused in the imprinting process. Currently, several techniques exist for thesynthesis of MIPs; however, they suffer from several drawbacks such asnon-specific adsorption, low adsorption capacity, low imprinting factor, lowsample throughput, and irreversible analyte loss leading to ineffective removalof the template and poor data quality. FIU inventors have developedchemical compositions and synthesis strategies to create MIPs via sol-gel processesusing organic, inorganic, or metallic target analyte. The resulting MIPs arehybrid organic-inorganic or inorganic three-dimensional network exhibiting highaffinity towards a target analyte and its structural analogs and remainindifferent to other molecules or species present in the same sample matrix. Anne Laure Schmitt Olivier aschmitt@fiu.edu 305-348-5948

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