Optimization of Replacement Heart Valve Leaflets

This invention provides geometry optimization of heart valve leaflets in transcatheter aortic valve replacement. To expand this technology to younger, lower-risk patients, long-term durability should match the current preferred treatment option, surgical aortic valve replacement (SAVR). Mechanical stress on heart valve leaflets is linked to leaflet degeneration. In this technology, parametric optimization studies are used to model the stress effects on leaflet geometry, and to determine a preferred geometry to decrease the stress. CeCe Ging techtransfer@du.edu 303-871-4230