SLAMF7, a critical receptor for phagocytosis of hematopoietic tumor cells during CD47-SIRP-alpha checkpoint blockage

This is the use of the SLAMF7 receptor for thestratification of patients who could benefit from a treatment blocking theCD47-SIRP-a axis, with the aim of increasing the phagocytosis of tumor cells.Alternative treatment would benefit patients with tumorsnegative for SLAMF7. Research suggests that patients with tumors expressing SLAMF7 would be more likely to respond to SIRPα/CD47 blocking therapy: Jean-Claude Sabourin jean-claude.sabourin@univalor.ca (514) 340 8503

March 4, 2020

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SLAMF7, a critical receptor for phagocytosis of hematopoietic tumor cells during CD47-SIRP-alpha checkpoint blockage

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