UMI-173 Long-Term, Controlled Oxygenation Generation for Cellular and Biomaterial Applications

Various strategies have been developed forgenerating oxygen in situ for biological applications. Thesemethods include oxygen reservoirs, which are limited in scopeand duration; electrochemical generators of oxygen, which arecomplicated by the electronics involved; and oxygen tanks, whichrequire daily purging and refilling. Most applications are forwound healing and not for applications where oxygen releasemust be sustained for a period of a week or more. There is aneed for technology that allows for sustained and controlledrelease of oxygen in biological fluids. Suitable biocompatiblesubstrates are required to expand the applications beyond woundhealing to include cutting edge technology such as regenerativemedicine. Peter Gutenberg 305-243-4604

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